MnTE-2-PyP (chloride)

MnTE-2-PyP (BMX-010) chloride is a ROS scavenger and potent radioprotector. MnTE-2-PyP also is a manganese porphyrin, protects normal prostate tissue from radiation damage. MnTE-2-PyP can be used for the research of diabetic prostate cancer[1].

Product Specifications

CAS Number

[219818-60-7]

Product Name Alternative

BMX-010 (chloride)

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mnte-2-pyp-chloride.html

Purity

95.00

Solubility

H2O : 12.5 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

[Cl-][Mn+3]123[N-]4C5=C(C6=CC=CC=[N+]6CC)C7=[N]1C(C=C7)=C(C8=CC=CC=[N+]8CC)C9=CC=C(C(C%10=CC=CC=[N+]%10CC)=C%11[N]3=C(C=C%11)C(C%12=CC=CC=[N+]%12CC)=C4C=C5)[N-]29.[Cl-].[Cl-].[Cl-].[Cl-]

Molecular Formula

C48H44Cl5MnN8

Molecular Weight

965.12

References & Citations

[1]Arpita Chatterjee, et al. MnTE-2-PyP, a manganese porphyrin, reduces cytotoxicity caused by irradiation in a diabetic environment through the induction of endogenous antioxidant defenses. Redox Biol. 2020 Jul;34:101542.