TLR8 antagonist-1
Product Specifications
CAS Number
1111460-83-3
Target
TLR, NF-κB, MyD88
Related Pathways
Immunology/Inflammation, NF-κB
Bioactivity
TLR8 antagonist 1 (Compound 10) is a selective antagonist that can inhibit TLR8 mediated inflammation and signaling pathways. TLR8 antagonist 1 reduces MyD88 recruitment and inhibits NF - κ B and IRF pathways, exhibiting certain anti-inflammatory activity.
Smiles
O=C(NC1CCN(CC)CC1)C2=CC=C(OCC=3C(=NOC3C)C)C(OC)=C2
Molecular Formula
C21H29N3O4
Molecular Weight
387.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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