FZD4 Antibody
Product Specifications
Background
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.
NCBI Gene ID
8322
Swiss Prot
Q9ULV1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 37-222 of human FZD4 (NP_036325.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
22Rv1
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 70kDa
Fragment
IgG
Symbol
FZD4
Positive Control 2
SKOV3
Positive Control 3
293T
Positive Control 4
Mouse trachea
Positive Control 5
Mouse eye
NCBI Official Name
Frizzled class receptor 4
NCBI Organism
Homo sapiens
Other Product Names
FZD4, EVR1, FEVR, FZD4S, Fz-4, FzE4, GPCR, MGC34390, Fz4, hFz4, CD344
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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