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Thalidomide- (1- (3R-pyrrolidinylmethyl) piperazine) -Boc

Thalidomide- (1- (3R-pyrrolidinylmethyl) piperazine) -Boc is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

Product Specifications

CAS Number

[2229718-01-6]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C1N(C(=O)C=2C1=CC(=CC2)N3CCN(C[C@H]4CN(C(OC(C)(C)C)=O)CC4)CC3)C5C(=O)NC(=O)CC5

Molecular Formula

C27H35N5O6

Molecular Weight

525.61

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

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