Pomalidomide-NH-PEG6-amide-C2-CPI-1612
Product Specifications
Target
PROTACs
Related Pathways
PROTAC
Bioactivity
Pomalidomide-NH-PEG6-amide-C2-CPI-1612 (compound 22 (dCE-1) ) is a CBP/EP300 degrader. It consists of the CRBN ligand Pomalidomide, a 24-atom chain with 6 PEG units, and the HAT inhibitor CPI-1612. This compound exhibits antiproliferative effects on multiple myeloma cells LP1 (DC50 = 1.2 μM), MM1S, and various cancer cells, notably leukemia cells.
Molecular Formula
C57H68N10O12
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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