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Mouse Erbb2 Antibody

Product Specifications

Background

Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Binds to the 5'-TCAAATTC-3' sequence in the MT-CO2 promoter and activates its transcription (By similarity) .

NCBI Gene ID

13866

Swiss Prot

P70424

Accession Number

P70424

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Erbb2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-559 amino acids from the Central region of mouse Erbb2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=58-126

Calculated Molecular Weight

139 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Erbb2

NCBI Official Name

Receptor tyrosine-protein kinase erbB-2

NCBI Organism

Mus musculus

Background Reference 01

Cabodi, S., et al. FASEB J. 24 (10) :3796-3808 (2010)

Background Reference 02

Johnson, E., et al. J. Biol. Chem. 285 (38) :29491-29501 (2010)

Background Reference 03

Huck, L., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (35) :15559-15564 (2010)

Background Reference 04

Chuang, T.D., et al. J. Biol. Chem. 285 (31) :23598-23606 (2010)

Other Product Names

Receptor tyrosine-protein kinase erbB-2, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, p185erbB2, CD340, Erbb2, Kiaa3023, Neu

Tested Applications

WB

Physical Properties

Liquid

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