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Falcarindiol

Product Specifications

CAS Number

55297-87-5

Target

JAK, STAT, NOD, NOS

Related Pathways

Tyrosine Kinase/Adaptors, Immunology/Inflammation, Stem Cells, NF-κB, JAK/STAT signaling, Chromatin/Epigenetic, Angiogenesis

Purity

0.9938

Bioactivity

Falcarindiol is an orally active natural polyacetylene compound exhibiting anti-inflammatory and antiproliferative properties. It inhibits NO production in LPS-induced mouse macrophages, reduces tyrosine phosphorylation of JAK1 and JAK2, and modulates STAT1 nuclear translocation, thereby suppressing iNOS expression.

Smiles

C([C@H](/C=C\CCCCCCC)O)#CC#C[C@H](C=C)O

Molecular Formula

C17H24O2

Molecular Weight

260.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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