Falcarindiol
Product Specifications
CAS Number
55297-87-5
Target
JAK, STAT, NOD, NOS
Related Pathways
Tyrosine Kinase/Adaptors, Immunology/Inflammation, Stem Cells, NF-κB, JAK/STAT signaling, Chromatin/Epigenetic, Angiogenesis
Purity
0.9938
Bioactivity
Falcarindiol is an orally active natural polyacetylene compound exhibiting anti-inflammatory and antiproliferative properties. It inhibits NO production in LPS-induced mouse macrophages, reduces tyrosine phosphorylation of JAK1 and JAK2, and modulates STAT1 nuclear translocation, thereby suppressing iNOS expression.
Smiles
C([C@H](/C=C\CCCCCCC)O)#CC#C[C@H](C=C)O
Molecular Formula
C17H24O2
Molecular Weight
260.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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