Falcarindiol
Product Specifications
CAS Number
55297-87-5
Target
JAK, STAT, NOD, NOS
Related Pathways
Tyrosine Kinase/Adaptors, Immunology/Inflammation, Stem Cells, NF-κB, JAK/STAT signaling, Chromatin/Epigenetic, Angiogenesis
Purity
0.9938
Bioactivity
Falcarindiol is an orally active natural polyacetylene compound exhibiting anti-inflammatory and antiproliferative properties. It inhibits NO production in LPS-induced mouse macrophages, reduces tyrosine phosphorylation of JAK1 and JAK2, and modulates STAT1 nuclear translocation, thereby suppressing iNOS expression.
Smiles
C([C@H](/C=C\CCCCCCC)O)#CC#C[C@H](C=C)O
Molecular Formula
C17H24O2
Molecular Weight
260.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
abx449269 100 µg
Receptor Tyrosine Kinase Like Orphan Receptor 1 (ROR1) Antibody (PerCP)
Sign In for Pricing
View Details 
038994-APC 200 µL
NKX1-1, ID (NKX1-1, HPX153, NK1 transcription factor-related protein 1, Homeobox protein 153, Homeobox protein SAX-2, NKX-1.1) (APC) discontinued
Sign In for Pricing
View Details