IUB0271 hydrochloride

IUB0271 (acyl-GIP) hydrochloride is a long-acting acylated glucose-dependent insulinotropic polypeptide (GIP) . This compound enhances cFos neuron activity in the hypothalamic feeding centers of DIO mouse models, resulting in reduced body weight, food intake, and blood glucose levels, effects that rely on CNS-GIPR signaling. IUB0271 hydrochloride is applicable in research on type 2 diabetes (T2DM) and obesity.