ML753286
Product Specifications
CAS Number
1699720-89-2
Target
BCRP, AMPK
Related Pathways
PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Membrane transporter/Ion channel
Bioactivity
ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions. ML753286 is an orally active and selective inhibitor of BCRP (IC50: 0.6 μM) . It is also stable in plasma across species.
Smiles
[H][C@]12Cc3c([nH]c4cc(OC)ccc34)[C@H](CC(C)C)N1C(=O)[C@H](C)NC2=O
Molecular Formula
C20H25N3O3
Molecular Weight
355.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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