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Inavolisib

Product Specifications

CAS Number

2060571-02-8

Target

PI3K, Apoptosis

Related Pathways

Apoptosis, PI3K/Akt/mTOR signaling

Purity

0.999

Bioactivity

Inavolisib (GDC-0077) is an orally available selective PI3Kα inhibitor with an IC50 value of 0.038 nM.It exerts its activity by binding to the ATP-binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3.

Smiles

C[C@H](Nc1ccc2-c3nc(cn3CCOc2c1)N1[C@@H](COC1=O)C(F)F)C(N)=O

Molecular Formula

C18H19F2N5O4

Molecular Weight

407.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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