DS-437
Product Specifications
CAS Number
1674364-87-4
Target
Histone Methyltransferase|||Others
Related Pathways
Chromatin/Epigenetic|||Others
Bioactivity
DS-437 is a dual PRMT5/7 inhibitor with IC50 values of 6 ?M and also inhibits DNMT3A and DNMT3B with IC50 values of 52 ?M and 62 ?M, respectively. Additionally, DS-437 inhibits the methylation of FOXP3.
Smiles
CCNC(=O)NCCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Molecular Formula
C15H23N7O4S
Molecular Weight
397.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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