Relebactam

Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases and KPC) and class C (AmpC) enzymes. Relebactam shows antibacterial activity[1].

Product Specifications

CAS Number

[1174018-99-5]

Product Name Alternative

MK-7655

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Bacterial; Beta-lactamase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Relebactam.html

Purity

99.86

Solubility

DMSO : 175 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

O=S(ON1[C@]2([H])CC[C@@H](C(NC3CCNCC3)=O)[N@@](C2)C1=O)(O)=O

Molecular Formula

C12H20N4O6S

Molecular Weight

348.38

Precautions

H315, H319, H320

References & Citations

[1]Lapuebla A, et al. Activity of Imipenem with Relebactam against Gram-Negative Pathogens from New York City. Antimicrob Agents Chemother. 2015 Aug;59 (8) :5029-31.|[2]Bush K. A resurgence of β-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens. Int J Antimicrob Agents. 2015 Nov;46 (5) :483-93.