Apoptosis inducer 40
Apoptosis inducer 40 is an apoptosis inducer. Apoptosis inducer 40 exhibits potent cytotoxic effects against jurkat and NB4 cells with IC50 values of 4.5 μM and 3.6μM. Apoptosis inducer 40 induces apoptosis and arrests cell cycle. Apoptosis inducer 40 can be used for the research of cancer, such as acute myeloid leukemia (AML) [1].
Product Specifications
CAS Number
[83800-90-2]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1NC(C2=CC=CC(Cl)=C2Cl)=NC3=CC=CC=C13
Molecular Formula
C14H8Cl2N2O
Molecular Weight
291.13
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Antoniolli G, et al. Synthesis and Evaluation of 2‑Substituted Quinazolin-4 (3H) ‑ones as Potential Antileukemic Agents. ACS Omega. 2025 Aug 1;10 (31) :34882-34894.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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