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Apoptosis inducer 40

Apoptosis inducer 40 is an apoptosis inducer. Apoptosis inducer 40 exhibits potent cytotoxic effects against jurkat and NB4 cells with IC50 values of 4.5 μM and 3.6μM. Apoptosis inducer 40 induces apoptosis and arrests cell cycle. Apoptosis inducer 40 can be used for the research of cancer, such as acute myeloid leukemia (AML) [1].

Product Specifications

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Apoptosis

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C1NC(C2=CC=CC(Cl)=C2Cl)=NC3=CC=CC=C13

Molecular Formula

C14H8Cl2N2O

Molecular Weight

291.13

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Antoniolli G, et al. Synthesis and Evaluation of 2‑Substituted Quinazolin-4 (3H) ‑ones as Potential Antileukemic Agents. ACS Omega. 2025 Aug 1;10 (31) :34882-34894.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W965550/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

CAS Number

[83800-90-2]

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