Grossamide
Grossamide is a natural product that can be isolated from fructus cannabis, the dried fruit of Cannabis sativa L.. Grossamide has anti-neuroinflammatory effects[1].
Product Specifications
CAS Number
[80510-06-1]
UNSPSC
12352005
Target
Interleukin Related; MyD88; NF-κB; TNF Receptor; Toll-like Receptor (TLR)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/grossamide.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1C2=CC(/C=C/C(NCCC(C=C3)=CC=C3O)=O)=CC(OC)=C2O[C@]1([H])C(C=C4)=CC(OC)=C4O)NCCC(C=C5)=CC=C5O
Molecular Formula
C36H36N2O8
Molecular Weight
624.68
References & Citations
[1]Luo Q, et al. Anti-neuroinflammatory effects of grossamide from hemp seed via suppression of TLR-4-mediated NF-κB signaling pathways in lipopolysaccharide-stimulated BV2 microglia cells. Mol Cell Biochem. 2017 Apr;428 (1-2) :129-137.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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