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Ube4A Recombinant Rabbit Monoclonal Antibody [JE56-68]

This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

E4 antibody KIAA0126 antibody MGC133315 antibody UBE4A antibody UBE4A_HUMAN antibody Ubiquitin conjugation factor E4 A antibody ubiquitination factor E4A (UFD2 homolog yeast) antibody Ubiquitination factor E4A antibody UBOX2 antibody UFD2 antibody UFD2 homolog antibody UFD2b antibody

Abbreviation

UBE4A

Swiss Prot

Q14139 Human, Q6P7A2 Rat

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Rat

Immunogen

Recombinant protein within human Ube4A aa 1-100.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

Rat brain tissue lysates, HepG2 cell lysate, 293T cell lysate, PANC-1, SKOV-3, SW620, human small intestine tissue, HepG2.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000;IF-Cell: 1:50-1:100;IHC-P: 1:50-1:200;FC: 1:500-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 123 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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