Ube4A Recombinant Rabbit Monoclonal Antibody [JE56-68]
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Product Specifications
Product Name Alternative
Abbreviation
UBE4A
Swiss Prot
Q14139 Human, Q6P7A2 Rat
Cellular Locus
Cytoplasm.
Host
Rabbit
Species Reactivity
Human,Rat
Immunogen
Recombinant protein within human Ube4A aa 1-100.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Rat brain tissue lysates, HepG2 cell lysate, 293T cell lysate, PANC-1, SKOV-3, SW620, human small intestine tissue, HepG2.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000;IF-Cell: 1:50-1:100;IHC-P: 1:50-1:200;FC: 1:500-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 123 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
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