GluR2 Recombinant Rabbit Monoclonal Antibody [JU20-43]
Lonotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
GluR-2, GluA2, GRIA2, GLUR2
Swiss Prot
P42262 Human, P23819 Mouse, P19491 Rat
Cellular Locus
Cell membrane, postsynaptic cell membrane, postsynaptic density membrane, endoplasmic reticulum membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human GluR2 aa 181-230 / 883.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, IP
Positive Control
Rat brain lysates, N2A, SH-SY5Y, rat brain tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 99 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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