GluR2 Recombinant Rabbit Monoclonal Antibody [JU20-43]

Lonotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

AMPA 2 antibody AMPA selective glutamate receptor 2 antibody AMPA-selective glutamate receptor 2 antibody AMPA2 antibody GluA2 antibody GLUR 2 antibody GLUR B antibody GluR K2 antibody GluR-2 antibody GluR-B antibody GluR-K2 antibody GLUR2 antibody GLURB antibody Glutamate receptor 2 antibody Glutamate receptor ionotropic AMPA 2 antibody Glutamate receptor ionotropic antibody Gria2 antibody GRIA2_HUMAN antibody HBGR2 antibody

Abbreviation

GluR-2, GluA2, GRIA2, GLUR2

Swiss Prot

P42262 Human, P23819 Mouse, P19491 Rat

Cellular Locus

Cell membrane, postsynaptic cell membrane, postsynaptic density membrane, endoplasmic reticulum membrane.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide within Human GluR2 aa 181-230 / 883.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, IP

Positive Control

Rat brain lysates, N2A, SH-SY5Y, rat brain tissue, mouse brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 99 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes

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