EAAT3 Recombinant Rabbit Monoclonal Antibody [JU39-69]

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. Mediates Cl- flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na+ symport. Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. Negatively regulated by ARL6IP5.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

EAA3_HUMAN antibody EAAC 1 antibody EAAC1 antibody EAAT 3 antibody Excitatory amino acid carrier 1 antibody Excitatory amino acid carrier1 antibody Excitatory amino acid transporter 3 antibody Excitatory amino acid transporter3 antibody Excitatory amino-acid carrier 1 antibody GLUTAMATE TRANSPORTER, HIGH-AFFINITY antibody MEAAC 1 antibody MEAAC1 antibody Neuronal and epithelial glutamate transporter antibody REAAC 1 antibody REAAC1 antibody Slc1 a1 antibody Slc1a 1 antibody SLC1A1 antibody Sodium dependent glutamate/aspartate transporter 3 antibody Sodium-dependent glutamate/aspartate transporter 3 antibody Solute carrier family 1 (neuronal / epithelial high affinity glutamate transporter, system Xag), member 1 antibody SOLUTE CARRIER FAMILY 1 (NEURONAL/EPITHELIAL HIGH AFFINITY GLUTAMATE TRANSPORTER), MEMBER 1 antibody Solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 antibody Solute carrier family 1 member 1 antibody Solute carrier family 1, member 1 antibody

Abbreviation

SLC1A1, EAAC1, EAAT3

Swiss Prot

P43005 Human, P51906 Mouse, P51907 Rat

Cellular Locus

Cell membrane.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse

Immunogen

Recombinant protein within Human EAAT3 aa 80-209 / 524.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC

Positive Control

Human brain tissue lysate, Human lung tissue lysate, SH-SY5Y, rat brain tissue, human tonsil tissue, human colon carcinoma tissue, human kidney tissue.