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Adiponectin Recombinant Rabbit Monoclonal Antibody [PSH05-48]

Adiponectin is a protein hormone that modulates a number of metabolic processes, including glucose regulation and fatty acid oxidation. Adiponectin is secreted from adipose tissue (and also from the placenta in pregnancy) into the bloodstream and is very abundant in plasma relative to many hormones. High adiponectin levels correlate with a lower risk of diabetes mellitus type 2. Plasma levels of adiponectin are lower in obese subjects than in lean subjects. Many studies have found adiponectin to be inversely correlated with body mass index in patient populations. However, a meta analysis was not able to confirm this association in healthy adults. Circulating adiponectin concentrations increase during caloric restriction in animals and humans, such as in patients with anorexia nervosa. Furthermore, a recent study suggests that adipose tissue within bone marrow, which increases during caloric restriction, contributes to elevated circulating adiponectin in this context.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

30 kDa adipocyte complement related protein antibody 30 kDa adipocyte complement-related protein antibody ACDC antibody Acrp 30 antibody ACRP30 antibody ADIPO_HUMAN antibody Adipocyte antibody Adipocyte C1q and collagen domain containing protein antibody Adipocyte complement related 30 kDa protein antibody Adipocyte complement related protein of 30 kDa antibody Adipocyte complement-related 30 kDa protein antibody adipocyte-specific secretory protein antibody Adiponectin antibody Adiponectin precursor antibody adiponectin, C1Q and collagen domain containing antibody Adipoq antibody Adipose most abundant gene transcript 1 antibody Adipose most abundant gene transcript 1 protein antibody Adipose specific collagen like factor antibody ADIPQTL1 antibody ADPN antibody APM 1 antibody apM-1 antibody APM1 antibody C1q and collagen domain-containing protein antibody GBP 28 antibody GBP28 antibody Gelatin binding protein antibody Gelatin binding protein 28 antibody gelatin-binding protein 28 antibody Gelatin-binding protein antibody OTTHUMP00000210047 antibody

Abbreviation

ADIPOQ, ACDC, ACRP30, APM1, GBP28

Swiss Prot

Q15848 Human, Q60994 Mouse,

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human Adiponectin aa 1-244 / 244.

Isotype

IgG

Clone

PSH05-48

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Tissue

Positive Control

Mouse white adipose tissue lysate, rat white adipose tissue lysate, human plasma lysates, human placenta tissue, human breast tissue, mouse breast tissue, rat skin tissue.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IHC-P: 1:200-1:1,000 ;IF-Tissue: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 26 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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