T3Inh-1
T3Inh-1 is a potent and selective inhibitor of ppGalNAc-T3 (IC50=7 μM) . T3Inh-1 reduces FGF23 hormone levels in both tissue cells and mice, without causing any toxic side effects. T3Inh-1 also prevents breast cancer cells. The enzyme ppGalNAc-T3 is implicated in at least two medically important pathways: cancer metastasis and stabilization of FGF23 (regulates phosphate levels in the bloodstream) [1].
Product Specifications
CAS Number
[50440-30-7]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/t3inh-1.html
Purity
99.93
Solubility
DMSO : 10 mg/mL (ultrasonic; adjust pH to 6 with HCl)
Smiles
O=C(NC1=CC=C(NC2=CC=NC=C2)C=C1)C3=CC=C(NC4=CC=NC5=CC=C([N+]([O-])=O)C=C45)C=C3
Molecular Formula
C27H20N6O3
Molecular Weight
476.49
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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