SR-302
SR-302, a chemical probe, is a potent and selectivity DDR/p38 inhibitor, with IC50 values of 0.125, 0.023 and 0.018 μM for p38α, DDR1 and DDR2, respectively. SR-302 can be used for the research of fibrotic disorders, such as renal and pulmonary fibrosis, atherosclerosis, and various forms of cancer[1].
Product Specifications
CAS Number
[2771319-74-3]
UNSPSC
12352005
Target
Discoidin Domain Receptor; p38 MAPK
Related Pathways
MAPK/ERK Pathway; Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Purity
98.51
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CS(N(CCC1)CC1NC([C@H](CCC2CCCCC2)NC(C(C=C3)=CC=C3CNC(C4=CN=C5N4C=CC=C5)=O)=O)=O)(=O)=O
Molecular Formula
C32H42N6O5S
Molecular Weight
622.78
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-167208/SR-302-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DDR1; DDR2; p38α
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
