Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-CD146 Antibody / MCAM

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. CD146 expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. It is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

P43121

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human protein was used as the immunogen for the anti-CD146 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

SPM620

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the anti-CD146 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This anti-CD146 antibody is available for research use only.

Storage Conditions

Store the anti-CD146 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Location

Cell surface, cytoplasm

Image Legend

IHC: Formalin-fixed, paraffin-embedded human melanoma stained with anti-CD146 antibody (SPM620)

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Cell Navigator® Fluorimetric Lipid Droplet Assay Kit *Green Fluorescence*
22730-AAT 200 Tests

Cell Navigator® Fluorimetric Lipid Droplet Assay Kit *Green Fluorescence*

Sign In for Pricing
View Details
Dishevelled 2 Recombinant Rabbit Monoclonal Antibody [PSH04-07]
HA722088 100 µL

Dishevelled 2 Recombinant Rabbit Monoclonal Antibody [PSH04-07]

Sign In for Pricing
View Details
AF/LE Purified Anti-Mouse IL-6 Antibody[MP5-20F3]
E-AB-F12070-01 100 µg

AF/LE Purified Anti-Mouse IL-6 Antibody[MP5-20F3]

Sign In for Pricing
View Details
AF/LE Purified Anti-Mouse IL-6 Antibody[MP5-20F3]
E-AB-F12070-02 1 mg

AF/LE Purified Anti-Mouse IL-6 Antibody[MP5-20F3]

Sign In for Pricing
View Details
AF/LE Purified Anti-Mouse IL-6 Antibody[MP5-20F3]
E-AB-F12070-03 5 mg

AF/LE Purified Anti-Mouse IL-6 Antibody[MP5-20F3]

Sign In for Pricing
View Details
AF/LE Purified Anti-Mouse IL-6 Antibody[MP5-20F3]
E-AB-F12070-04 25 mg

AF/LE Purified Anti-Mouse IL-6 Antibody[MP5-20F3]

Sign In for Pricing
View Details