Dishevelled 2 Recombinant Rabbit Monoclonal Antibody [PSH04-07]

Segment polarity protein dishevelled homolog DVL-2 is a protein that in humans is encoded by the DVL2 gene. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. DVL2 has been shown to interact with Zinc finger protein 165, DAB2 and Arrestin beta 1.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Dishevelled 2 (homologous to Drosophila dsh) antibody Dishevelled dsh homolog 2 antibody dishevelled segment polarity protein 2 antibody Dishevelled-2 antibody Dishevelled2 antibody DSH homolog 2 antibody DVL 2 antibody Dvl2 antibody DVL2_HUMAN antibody Segment polarity protein dishevelled homolog DVL 2 antibody Segment polarity protein dishevelled homolog DVL-2 antibody Segment polarity protein dishevelled homolog DVL2 antibody

Abbreviation

DVL2

Swiss Prot

O14641 Human, Q60838 Mouse,

Cellular Locus

Cell membrane, Cytoplasm, cytosol, Cytoplasmic vesicle, Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human Dishevelled 2 aa 550-700 / 736.

Isotype

IgG

Clone

PSH04-07

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

HeLa cell lysate, 293T cell lysate, MCF7 cell lysate, NCI-H1299 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, HeLa, NIH/3T3, human colon tissue, mouse colon tissue, rat colon tissue.