Recombinant LATS1 Protein

<strong>Recombinant LATS1 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017579_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 128.1 kDa_x000D_ <strong>Supplied as:</strong> SOLUTION_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Large Tumor Suppressor Kinase 1, WARTS Protein Kinase_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Qian M, Yan F, Wang W, Du J, Yuan T, Wu R, Zhao C, Wang J, Lu J, Zhang B, Lin N, Dong X, Dai X, Dong X, Yang B, Zhu H, He Q. Deubiquitinase JOSD2 stabilizes YAP/TAZ to promote cholangiocarcinoma progression Acta Pharm Sin B. 2021 Dec;11(12):4008-4019._x000D_ 2: Deng J, Zhang W, Liu S, An H, Tan L, Ma L. LATS1 suppresses proliferation and invasion of cervical cancer Mol Med Rep. 2017 Apr;15(4):1654-1660._x000D_ 3: Xia H, Qi H, Li Y, Pei J, Barton J, Blackstad M, Xu T, Tao W. LATS1 tumor suppressor regulates G2/M transition and apoptosis Oncogene. 2002 Feb 14;21(8):1233-41._x000D_ 4: Wan W, Sun B, Yang S, Zhou C, Li Y. Expression of LATS1 in head and neck squamous cell carcinoma and its effect on tumor cell proliferation and invasion Cell Mol Biol (Noisy-le-grand). 2022 May 31;68(5):135-140._x000D_ 5: Lorthongpanich C, Jiamvoraphong N, Supraditaporn K, Klaihmon P, U-Pratya Y, Issaragrisil S. The Hippo pathway regulates human megakaryocytic differentiation Thromb Haemost. 2017 Jan 5;117(1):116-126._x000D_ 6: Jin L, Jin A, Wang L, Qi X, Jin Y, Zhang C, Niu M. NRP1 Induces Enhanced Stemness and Chemoresistance in Glioma Cells via YAP Biol Pharm Bull. 2024;47(1):166-174._x000D_ 7: Bothos J, Tuttle RL, Ottey M, Luca FC, Halazonetis TD. Human LATS1 is a mitotic exit network kinase Cancer Res. 2005 Aug 1;65(15):6568-75._x000D_ 8: Pisarska MD, Kuo FT, Bentsi-Barnes IK, Khan S, Barlow GM. LATS1 phosphorylates forkhead L2 and regulates its transcriptional activity Am J Physiol Endocrinol Metab. 2010 Jul;299(1):E101-9._x000D_ 9: Chen Z, Shi H, Sun S, Xu H, Cao D, Luo J. MicroRNA-181b suppresses TAG via target IRS2 and regulating multiple genes in the Hippo pathway Exp Cell Res. 2016 Oct 15;348(1):66-74._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/30250159">10: Kedan A, Verma N, Saroha A, Shreberk-Shaked M, Müller AK, Nair NU, Lev S. PYK2 negatively regulates the Hippo pathway in TNBC by stabilizing TAZ protein Cell Death Dis. 2018 Sep 24;9(10):985. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant LATS1 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>