Tert-Butyl 11-aminoundecanoate
Tert-Butyl 11-aminoundecanoate (compound 6b) is a PROTAC linker, which refers to the PEG composition. tert-Butyl 11-aminoundecanoate can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Product Specifications
CAS Number
[220851-29-6]
UNSPSC
12352211
Hazard Statement
H315, H318, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tert-butyl-11-aminoundecanoate.html
Purity
99.39
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC(C)(C)C)CCCCCCCCCCN
Molecular Formula
C15H31NO2
Molecular Weight
257.41
Precautions
H315, H318, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
Available Sizes
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