DYRK3 Antibody (N-term) [APR05926G]
Product Specifications
Background
Tissue Location: Isoform 1: Highly expressed in testis and in hematopoietic tissue such as fetal liver, and bone marrow (PubMed:10779429) . Isoform 1: Predominant form in fetal liver and bone marrow (PubMed:10779429) . Isoform 1: Present at low levels in heart, pancreas, lymph node and thymus (PubMed:10779429) . Isoform 2: Highly expressed in testis and in hematopoietic tissue such as fetal liver, and bone marrow (PubMed:10779429) . Isoform 2: Predominant form in testis. Isoform 2: Present at low levels in heart, pancreas, lymph node and thymus (PubMed:10779429) .
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DYRK3 Antibody (N-term) [APR05926G].
Synonyms
Dual specificity tyrosine-phosphorylation-regulated kinase 3, Regulatory erythroid kinase, REDK, DYRK3
Gene Name
HGNC:3094
Gene ID
8444
UniProt
O43781
Chromosomal Location
Nucleus. Cytoplasm. Nucleus speckle. Cytoplasmic granule. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Associates with membraneless organelles in the cytoplasm and nucleus (PubMed:29973724) . Shuttles between cytoplasm and stress granules (PubMed:20167603) . Localized predominantly on distinct speckles distributed throughout the cytoplasm of the cell (PubMed:20167603) . At low concentration, showns a homogeneous distribution throughout the cytoplasm and does not condense in speckles. During oxidative and osmotic stress, localizes to stress granules (PubMed:20167603) .
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Function
299737249748265296349192997372429973724299737242341522723415227107794291077942920167603
Molecular Weight
65714
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8444
Uniprot URL
https://www.uniprot.org/uniprot/O43781
Available Sizes
Frequently Asked Questions
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