Β-Glucuronidase Inhibitor

<strong>β-Glucuronidase Inhibitor</strong>_x000D_ <strong>Catalog number:</strong> B2019151_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 425.54 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> β-Glucuronidase Inhibitor, 1-((6,8-Dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-3-(4-ethoxyphenyl)-1-(2-hydroxyethyl)thiourea_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kerins A, Koszyczarek M, Smith C, Butler P, Riley R, Madgula V, Naik N, Redinbo MR, Wilson ID. The in vitro metabolism and in vivo pharmacokinetics of the bacterial β-glucuronidase inhibitor UNC10201652 Xenobiotica. 2022 Aug;52(8):904-915._x000D_ 2: Rosay T, Jimenez AG, Sperandio V. Glucuronic acid confers colonization advantage to enteric pathogens Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2400226121._x000D_ 3: Lee HW, Choo MK, Bae EA, Kim DH. Beta-glucuronidase inhibitor tectorigenin isolated from the flower of Pueraria thunbergiana protects carbon tetrachloride-induced liver injury Liver Int. 2003 Aug;23(4):221-6._x000D_ 4: Kreamer BL, Siegel FL, Gourley GR. A novel inhibitor of beta-glucuronidase: L-aspartic acid Pediatr Res. 2001 Oct;50(4):460-6._x000D_ 5: Behera D, Jain P, Kurawattimath V, Gowda N. Effect of Saccharolactone on CYP-mediated Metabolism of Xenobiotics Drug Metab Bioanal Lett. 2023;16(2):121-132._x000D_ 6: Wang P, Jia Y, Wu R, Chen Z, Yan R. Human gut bacterial β-glucuronidase inhibition: An emerging approach to manage medication therapy Biochem Pharmacol. 2021 Aug;190:114566._x000D_ 7: Awolade P, Cele N, Kerru N, Gummidi L, Oluwakemi E, Singh P. Therapeutic significance of β-glucuronidase activity and its inhibitors: A review Eur J Med Chem. 2020 Feb 1;187:111921._x000D_ 8: Rasmussen TS, Koldsø H, Nakagawa S, Kato A, Schiøtt B, Jensen HH. Synthesis of uronic-noeurostegine--a potent bacterial β-glucuronidase inhibitor Org Biomol Chem. 2011 Oct 26;9(22):7807-13._x000D_ 9: Sakamoto W. Immunochemical study of beta-glucuronidase inhibitor from porcine sublingual gland. Interaction of beta-glucuronidase inhibitor with alpha2-macroglobulin Biochim Biophys Acta. 1975 Dec 5;411(2):195-201._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/36190839">10: Ikuta H, Shimada H, Sakamoto K, Nakamura R, Kawase A, Iwaki M. Species differences in liver microsomal hydrolysis of acyl glucuronide in humans and rats Xenobiotica. 2022 Jul;52(7):653-660. </a>_x000D_ _x000D_ <strong>Products Related to β-Glucuronidase Inhibitor can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>