BANP antibody
Product Specifications
Background
Controls V(D)J recombination during T-cell development by repressing T-cell receptor(TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta(S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest(By similarity).
Synonyms
Protein BANP|BEN domain-containing protein 1|Btg3-associated nuclear protein|Scaffold/matrix-associated region-1-binding protein|BANP|BEND1|SMAR1
Gene ID
54971
UniProt
Q8N9N5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
BTG3 associated nuclear protein
Target
BANP
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
56 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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