Mouse IL-1 alpha Recombinant Protein
IL-1 alpha (IL-1α, IL-1F1) is a member of the interleukin 1 family of cytokines. IL-1 alpha is an inflammatory cytokine active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. Mouse IL-1 alpha Recombinant Protein is purified interleukin-1 alpha cytokine produced in yeast.
Product Specifications
Synonyms
Interleukin-1 alpha; IL-1 alpha; Il1a
Gene Name
IL1A
UniProt
P01582
Source
Yeast
Sequence
[object Object]
Applications
Cell Culture
Field of Research
Cancer, Cytokines, Immunology, Innate Immunity, Interleukins, Tumor Immunology
Purification
Ion-exchange chromatography.
Bioactivity
In testing.
Form
Lyophilized
Function
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Subcellular Location
Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
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