DMRT2 Antibody
The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene (s) on chr 9. Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity) .
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/million cells, Western blot: 1-2 µg/mL
UniProt
Q9Y5R5
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human DMRT2 protein was used as the immunogen for the DMRT2 antibody.
Clonality
Monoclonal
Isotype
IgG2b
Clone
PCRP-DMRT2-1B11
Applications
FACS, WB
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the DMRT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This DMRT2 antibody is available for research use only.
Storage Conditions
Aliquot the DMRT2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.nsjbio.com/tds-pdf/dmrt2-antibody-pcrp-dmrt2-1b11-v9601
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the DMRT2 antibody should be determined by the researcher.
Location
Nucleus
Image Legend
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
