Bestatin-d7 (hydrochloride)
Bestatin-d7 (hydrochloride) is deuterium labeled Bestatin (hydrochloride) . Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N) /APN and leukotriene A4 hydrolase, used for cancer research.
Product Specifications
Product Name Alternative
Ubenimex-d7 (hydrochloride)
UNSPSC
12352005
Target
Aminopeptidase; Antibiotic; Bacterial; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Others
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Purity
97.73
Solubility
10 mM in DMSO
Smiles
O=C(O)[C@H](CC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])NC([C@@H](O)[C@H](N)CC1=CC=CC=C1)=O.Cl
Molecular Formula
C16H18D7ClN2O4
Molecular Weight
351.88
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Hossain A, et al. Protective effects of bestatin in the retina of streptozotocin-induced diabetic mice. Exp Eye Res. 2016 Aug;149:100-6|[3]Lis M, et al. The effects of bestatin on humoral response to sheep erythrocytes in non-treated and cyclophosphamide-immunocompromised mice. Immunopharmacol Immunotoxicol. 2013 Feb;35 (1) :133-8|[4]Poloz Y, et al. Bestatin inhibits cell growth, cell division, and spore cell differentiation in Dictyostelium discoideum. Eukaryot Cell. 2012 Apr;11 (4) :545-57|[5]Qian X, et al. Inhibition of p38 MAPK Phosphorylation Is Critical for Bestatin to Enhance ATRA-Induced Cell Differentiation in Acute Promyelocytic Leukemia NB4 Cells. Am J Ther. 2016 May-Jun;23 (3) :e680-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
CD13
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb2932096-01 20 µg
Recombinant Acinetobacter baumannii Large-conductance mechanosensitive channel (mscL)
Sign In for Pricing
View Details orb2932096-02 100 µg
Recombinant Acinetobacter baumannii Large-conductance mechanosensitive channel (mscL)
Sign In for Pricing
View Details 
EK10F85-01 48 Test
Bovine TNF Receptor Superfamily Member 17 (TNFRSF17) ELISA Kit-Sandwich
Sign In for Pricing
View Details EK10F85-02 96 Tests
Bovine TNF Receptor Superfamily Member 17 (TNFRSF17) ELISA Kit-Sandwich
Sign In for Pricing
View Details