Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

AChE-IN-21

AChE-IN-21 (Compound I-8) is a potent, selective and orally active AChE inhibitor with an IC50 of 2.66 nM. AChE-IN-21 displays excellent BBB permeability in vitro[1].

Product Specifications

CAS Number

2413656-04-7

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ache-in-21.html

Solubility

10 mM in DMSO

Smiles

O=C1O/C(C2=C1C=C(OC)C(OC)=C2)=C\CCCCCN(CC3=CC=CC=C3)C

Molecular Formula

C24H29NO4

Molecular Weight

395.49

References & Citations

[1]Luo L, et al. Design, synthesis and evaluation of phthalide alkyl tertiary amine derivatives as promising acetylcholinesterase inhibitors with high potency and selectivity against Alzheimer's disease. Bioorg Med Chem. 2020 Apr 15;28 (8) :115400.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AChE; BChE

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

DLL4 Protein (C-human IgG1-Fc, Human)
P520941 100 µg

DLL4 Protein (C-human IgG1-Fc, Human)

Sign In for Pricing
View Details
Recombinant Human Atrial natriuretic peptide receptor 2 (NPR2), partial
CSB-MP016024HU-01 20 µg

Recombinant Human Atrial natriuretic peptide receptor 2 (NPR2), partial

Sign In for Pricing
View Details
Recombinant Human Atrial natriuretic peptide receptor 2 (NPR2), partial
CSB-MP016024HU-02 100 µg

Recombinant Human Atrial natriuretic peptide receptor 2 (NPR2), partial

Sign In for Pricing
View Details
Recombinant Human Atrial natriuretic peptide receptor 2 (NPR2), partial
CSB-MP016024HU-03 1 mg

Recombinant Human Atrial natriuretic peptide receptor 2 (NPR2), partial

Sign In for Pricing
View Details
Recombinant Influenza A virus Matrix protein 2 (M)
orb2935402-01 20 µg

Recombinant Influenza A virus Matrix protein 2 (M)

Sign In for Pricing
View Details
Recombinant Influenza A virus Matrix protein 2 (M)
orb2935402-02 100 µg

Recombinant Influenza A virus Matrix protein 2 (M)

Sign In for Pricing
View Details