DDO-02001

DDO-02001 is a moderately potent Kv1.5 potassium channel inhibitor with an IC50 value of 17.7 μM. DDO-02001 can be used for researching anti-arrhythmia[1].

Product Specifications

CAS Number

[1186049-49-9]

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ddo-02001.html

Solubility

10 mM in DMSO

Smiles

O=C(C1CCN(CC2=CC=CC=C2)CC1)NC3=CC=C(OC)C=C3

Molecular Formula

C20H24N2O2

Molecular Weight

324.42

References & Citations

[1]Zhao L, et al. Design, synthesis, and biological evaluation of arylmethylpiperidines as Kv1.5 potassium channel inhibitors. J Enzyme Inhib Med Chem. 2022;37 (1) :462-471.