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Mal-NO2-Ph-PEG12-NHS

Mal-NO2-Ph-PEG12-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

UNSPSC

12352005

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mal-no2-ph-peg12-nhs.html

Solubility

10 mM in DMSO

Smiles

O=C(C=CC1=O)N1C2=C([N+]([O-])=O)C=C(CC(NCCOCCOCCC(ON3C(CCC3=O)=O)=O)=O)C=C2.[11]

Molecular Formula

C42H62N4O21

Molecular Weight

959.00

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Curated Selection

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