Research Grade Ulocuplumab

Ulocuplumab (BMS-936564) isafirst-in-classfullyhumanIgG4monoclonalanti-CXCR4antibodythatinhibitsthebindingofCXCR4toCXCL12.TheCXCR4/CXCL12 (SDF-1) axishasbeenknownformanyyearsasacriticalregulatoroftumorproliferation, cell, aswellasmigrationintoandoutofthebonemarrow.

Product Specifications

Product Name Alternative

BMS-936564, MDX-1338, MDX1338, CAS:1375830-34-4

Expression System

Mammalian Cells

Host

Human

Target

Stromalcell-derivedfactor1receptor, LCR1, HM89, LPS-associatedprotein3, LAP-3, CXC-R4, CXCR-4, SDF-1receptor, CD184, NPYRL, LESTR, Fusin, FB22, C-X-Cchemokinereceptortype4, CXCR4, Lipopolysaccharide-associatedprotein3, Leukocyte-derivedseventransmembranedomainreceptor

Clonality

Monoclonal

Applications

ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Purification

Protein A/G purified from cell culture supernatant.

Concentration

1.59mg/ml

Endotoxin

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Form

Liquid

Buffer

0.01M PBS, pH7.4.

Storage Conditions

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at4°C short term (1-2weeks) . Store at-20°C 12 months. Store at -285°C long term.