Research Grade Ulocuplumab
Ulocuplumab (BMS-936564) isafirst-in-classfullyhumanIgG4monoclonalanti-CXCR4antibodythatinhibitsthebindingofCXCR4toCXCL12.TheCXCR4/CXCL12 (SDF-1) axishasbeenknownformanyyearsasacriticalregulatoroftumorproliferation, cell, aswellasmigrationintoandoutofthebonemarrow.
Product Specifications
Product Name Alternative
BMS-936564, MDX-1338, MDX1338，CAS:1375830-34-4
Expression System
Mammalian Cells
Host
Human
Target
Stromalcell-derivedfactor1receptor, LCR1, HM89, LPS-associatedprotein3, LAP-3, CXC-R4, CXCR-4, SDF-1receptor, CD184, NPYRL, LESTR, Fusin, FB22, C-X-Cchemokinereceptortype4, CXCR4, Lipopolysaccharide-associatedprotein3, Leukocyte-derivedseventransmembranedomainreceptor
Clonality
Monoclonal
Applications
ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Purification
Protein A/G purified from cell culture supernatant.
Concentration
1.59 mg/mL
Purity
> 95% as determined by SDS-PAGE.
Form
Liquid
Buffer
0.01M PBS, pH7.4.
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at4°C short term (1-2weeks) . Store at-20°C 12 months. Store at -285°C long term.
Notes
For research use only. Not suitable for clinical or therapeutic use.
Species
Human
Available Sizes
Curated Selection
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