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Glucokinase activator 6

Glucokinase activator 6 (compound 9) is a potent glucokinase activator, with an EC50 of 0.09 μM. Glucokinase activator 6 can be used for type 2 diabetes (T2D) research[1].

Product Specifications

CAS Number

[480463-02-3]

UNSPSC

12352005

Target

Glucokinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/glucokinase-activator-6.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CN=C(C=C1)NC(C2=CC(OCCC3=CSC=C3)=CC(OC(C)C)=C2)=O)O

Molecular Formula

C22H22N2O5S

Molecular Weight

426.49

References & Citations

[1]Kumari V, et al. Comparative docking assessment of glucokinase interactions with its allosteric activators. Curr Chem Genomics. 2008 Dec 30;2:76-89.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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