BMS-193885
BMS-193885 is a selective neuropeptide Y1 receptor antagonist (Ki=3.3 nM) that competitively blocks the receptor to inhibit NPY-mediated appetite regulation signaling pathways, reduce food intake and inhibit weight gain. BMS-193885 has good blood-brain barrier penetration and is mainly used in the study of obesity and related metabolic diseases[1][2][3].
Product Specifications
CAS Number
186185-03-5
UNSPSC
12352005
Hazard Statement
H302
Target
Neuropeptide Y Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/bms-193885.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC(NC(NCCCN3CCC(C4=CC=CC(OC)=C4)CC3)=O)=C2)OC
Molecular Formula
C33H42N4O6
Molecular Weight
590.71
Precautions
H302
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NPY Y1 receptor
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Separin, Phosphorylated (Ser1501) (ESPL1, Separase, Caspase-like Protein ESPL1, Extra Spindle Poles-like 1 Protein, ESP1, KIAA0165) (MaxLight 550)
Separin, Phosphorylated (Ser1501) (ESPL1, Separase, Caspase-like Protein ESPL1, Extra Spindle Poles-like 1 Protein, ESP1, KIAA0165) (MaxLight 550)
Recombinant Staphylococcus epidermidis Lipoteichoic acid synthase (ltaS)