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ASIC1 rabbit pAb

This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012],

Product Specifications

Background

This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012]

UniProt

P78348

Swiss Prot

P78348

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide from human protein at AA range: 220-280

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; IHC-f; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000

Molecular Weight

55kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

55kD

Fragment

IgG

Subcellular Location

Cell membrane ; Multi-pass membrane protein . Localizes in synaptosomes at dendritic synapses of neurons. Colocalizes with DLG4 (By similarity) . .

Other Product Names

Acid-sensing ion channel 1 (ASIC1; Amiloride-sensitive cation channel 2, neuronal; Brain sodium channel 2; BNaC2)

Gene ID (Human)

41

Available Sizes

Frequently Asked Questions

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