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Frizzled-3 rabbit pAb

Frizzled class receptor 3 (FZD3) Homo sapiens This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010],

Product Specifications

Background

Frizzled class receptor 3 (FZD3) Homo sapiens This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia. [provided by RefSeq, Dec 2010]

Product Name Alternative

FZD3; Frizzled-3; Fz-3; hFz3

UniProt

Q9NPG1

Swiss Prot

Q9NPG1

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human FZD3. AA range:141-190

Target

Frizzled-3

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

76kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

76kD

Fragment

IgG

Subcellular Location

Membrane; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein . Cell surface . Apical cell membrane ; Multi-pass membrane protein. Colocalizes with FZD6 at the apical face of the cell (By similarity) . .

Other Product Names

FZD3; Frizzled-3; Fz-3; hFz3

Gene ID (Human)

7976

Available Sizes

Curated Selection

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