Glurate
Glurate (4-Acetylbutyric acid) is an acylating agent. Glurate can be used in the development of antiviral compounds, especially those targeting retroviruses such as herpes virus and HIV. Glurate can be used in the synthesis of acyclic nucleoside derivatives and 5-hydroxyhexanoic acid[1][2].
Product Specifications
CAS Number
3128-06-1
Product Name Alternative
4-Acetylbutyric acid; 5-Oxohexanoic acid; NSC-5281
UNSPSC
12352211
Hazard Statement
H315, H319
Target
Drug Intermediate; HIV
Type
Reference compound
Related Pathways
Anti-infection; Others
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/glurate.html
Concentration
10mM
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(=O)CCCC(=O)O
Molecular Formula
C6H10O3
Molecular Weight
130.14
Precautions
H315, H319
References & Citations
[1]Per Engelhardt, et al. Synthesis of acyclic nucleosides. Patent WO1997030052A1.|[2]Valentin H E, et al. Identification of 5-hydroxyhexanoic acid, 4-hydroxyheptanoic acid and 4-hydroxyoctanoic acid as new constituents of bacterial polyhydroxyalkanoic acids. Applied microbiology and biotechnology, 1996, 46: 261-267.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Frequently Asked Questions
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