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Daminozide

Daminozide (DMASA; DIMG; B 995), a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily. (In Vitro) :Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested (IC50=127 μM for KDM3A, or greater against other demethylases) . (In Vivo) :Daminozide (200-20000 ppm) has teratogenic and genotoxic effects on model organism Drosophila melanogaster.

Product Specifications

CAS Number

1596-84-5

Product Name Alternative

Alar | Aminozide | B 995 | DIMG | DMASA | Kylar | SADH | Succinic Acid

Purity

>98% (HPLC)

Solubility

Soluble in DMSO

Smiles

OC (CCC (NN (C) C) =O) =O

Molecular Formula

C6H12N2O3

Molecular Weight

160.17

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4- (2,2-dimethylhydrazinyl) -4-oxobutanoic acid

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