HODHBt
HODHBt (HOOBt) inhibits STAT5-SUMO interaction by blocking SUMOylation of phosphorylated STAT5. HODHBt enhances the magnitude of IL-15 signaling and significantly increases the natural killer (NK) cell cytotoxicity phenotype and function and the generation of cytokine-induced memory-like (CIML) natural killer (NK) cells. HODHBt can be used for research of HIV-infection and cancer[1].
Product Specifications
CAS Number
28230-32-2
Product Name Alternative
HOOBt
UNSPSC
12352005
Hazard Statement
H226, H303, H312+H332, H315, H319, H335, H360
Target
HIV; STAT
Type
Reference compound
Related Pathways
Anti-infection; JAK/STAT Signaling; Stem Cell/Wnt
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/hodhbt.html
Purity
99.97
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1N(O)N=NC2=CC=CC=C12
Molecular Formula
C7H5N3O2
Molecular Weight
163.14
Precautions
H226, H303, H312+H332, H315, H319, H335, H360
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT5
Available Sizes
Frequently Asked Questions
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