Daminozide
Daminozide (DMASA; DIMG; B 995), a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily. (In Vitro) :Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested (IC50=127 μM for KDM3A, or greater against other demethylases) . (In Vivo) :Daminozide (200-20000 ppm) has teratogenic and genotoxic effects on model organism Drosophila melanogaster.
Product Specifications
CAS Number
1596-84-5
Product Name Alternative
Alar | Aminozide | B 995 | DIMG | DMASA | Kylar | SADH | Succinic Acid
Purity
>98% (HPLC)
Solubility
Soluble in DMSO
Smiles
OC (CCC (NN (C) C) =O) =O
Molecular Formula
C6H12N2O3
Molecular Weight
160.17
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4- (2,2-dimethylhydrazinyl) -4-oxobutanoic acid
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