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EP1013

EP1013 (F1013) is a broad-spectrum caspase selective inhibitor, used in the research of type 1 diabetes[1].

Product Specifications

CAS Number

[223568-55-6]

Product Name Alternative

F1013

UNSPSC

12352005

Target

Caspase

Type

Reference compound

Related Pathways

Apoptosis

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/EP1013.html

Concentration

10mM

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)C[C@H](NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)C(CF)=O

Molecular Formula

C18H23FN2O6

Molecular Weight

382.38

References & Citations

[1]Emamaullee JA, et al. The caspase selective inhibitor EP1013 augments human islet graft function and longevity in marginal mass islet transplantation in mice. Diabetes. 2008 Jun;57 (6) :1556-66.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Caspase

Available Sizes

Curated Selection

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