(1S) -Calcitriol

(1S) -Calcitriol (1α,25-Dihydroxy-3-epi-vitamin-D3) is a natural metabolite of 1α,25-dihydroxyvitamin D3 (1α,25 (OH) 2D3) . (1S) -Calcitriol exhibits potent vitamin D receptor (VDR) -mediated actions such as inhibition of keratinocyte growth or suppression of parathyroid hormone secretion[1].

Product Specifications

CAS Number

[61476-45-7]

Product Name Alternative

1α,25-Dihydroxy-3-epi-vitamin-D3

UNSPSC

12352211

Target

VD/VDR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/1s-calcitriol.html

Purity

98.52

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)(O)C)([H])/C(CCC1)=C/C=C3C([C@H](C[C@H](C\3)O)O)=C

Molecular Formula

C27H44O3

Molecular Weight

416.64

References & Citations

[1]Steve Y Rhieu, et al. Metabolic stability of 3-epi-1α,25-dihydroxyvitamin D3 over 1 α 25-dihydroxyvitamin D3: metabolism and molecular docking studies using rat CYP24A1. J Cell Biochem. 2013 Oct;114 (10) :2293-305.