Antitumor agent-184
Antitumor agent-184 (compound 12aa) induces cell apoptosis, with the IC50s of 2.35 μM, 7.32 μM and 10.31 μM in B16-F10 cells, 4T1 cells and CT26 cells, respectively[1].
Product Specifications
CAS Number
3040164-45-9
UNSPSC
12352211
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-184.html
Smiles
N#CC(C/1=O)=C2N=C(N)C(C3=C(CCCC3)S4)=C4N2C1=C\C(C5=CC=CC=C5)=O
Molecular Formula
C22H16N4O2S
Molecular Weight
400.45
References & Citations
[1]Irina A Gorbunova, et al. Design and one-pot synthesis of new substituted pyrrolo[1,2-a]thieno[3,2-e]pyrimidine as potential antitumor agents: in vitro and in vivo studies. Bioorg Chem. 2024 Jul:148:107468.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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