TTP 22

TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM.

Product Specifications

CAS Number

[329907-28-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Casein Kinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/TTP-22.html

Purity

98.40

Solubility

DMSO : ≥ 51 mg/mL

Smiles

O=C(O)CCSC1=C(C(C2=CC=C(C)C=C2)=CS3)C3=NC=N1

Molecular Formula

C16H14N2O2S2

Molecular Weight

330.42

Precautions

H302, H315, H319, H335

References & Citations

[1]Golub AG, et al. Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin-4-ylthio) carboxylic acids as inhibitors of human protein kinase CK2. Eur J Med Chem. 2011 Mar;46 (3) :870-6.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CK2

Available Sizes

Curated Selection

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