TTP 22
TTP 22 is a potent CK2 inhibitor, with an IC50 of 100 nM and a Ki of 40 nM.
Product Specifications
CAS Number
[329907-28-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Casein Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/TTP-22.html
Purity
98.40
Solubility
DMSO : ≥ 51 mg/mL
Smiles
O=C(O)CCSC1=C(C(C2=CC=C(C)C=C2)=CS3)C3=NC=N1
Molecular Formula
C16H14N2O2S2
Molecular Weight
330.42
Precautions
H302, H315, H319, H335
References & Citations
[1]Golub AG, et al. Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin-4-ylthio) carboxylic acids as inhibitors of human protein kinase CK2. Eur J Med Chem. 2011 Mar;46 (3) :870-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK2
Available Sizes
Curated Selection
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Cytokeratin 13 (Type I Cytoskeletal 13, 47kD Cytokeratin, CK 13, CK-13, CK13, Cytokeratin 13, Cytokeratin-13, Cytokeratin13, K13, K1C13_HUMAN, Ka13, Keratin 13, Keratin, Keratin Type I Cytoskeletal 13, Keratin-13, Keratin13, KRT 13, Krt-1.13, Krt1-13, KRT13, MGC161462, MGC3781, Type I keratin Ka13)
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